W | 2022-04-23 | Whitby Town |  | 1-2 |  | Gainsborough | D42 | | |
D | 2022-04-18 | Gainsborough | | 2-2 |  | Grantham Town | D41 | | |
L | 2022-04-16 | Scarborough Athletic |  | 2-0 | | Gainsborough | D40 | | |
W | 2022-04-09 | Gainsborough | | 2-0 |  | Mickleover | D39 | | |
D | 2022-04-02 | Gainsborough | | 1-1 |  | South Shields | D38 | | |
L | 2022-03-26 | Hyde United |  | 1-0 | | Gainsborough | D37 | | |
W | 2022-03-22 | Atherton Collieries |  | 0-1 | | Gainsborough | D30 | | |
D | 2022-03-19 | Gainsborough | | 0-0 |  | Nantwich Town | D36 | | |
L | 2022-03-12 | Ashton United |  | 2-1 | | Gainsborough | D35 | | |
L | 2022-03-05 | Gainsborough | | 1-2 |  | Matlock Town | D25 | | |
W | 2022-02-26 | Gainsborough | | 3-1 |  | Lancaster City | D34 | | |
L | 2022-02-19 | Buxton |  | 1-0 | | Gainsborough | D33 | | |
W | 2022-02-12 | Gainsborough | | 3-2 |  | FC United of Manchester | D32 | | |
D | 2022-02-08 | Stalybridge Celtic |  | 1-1 | | Gainsborough | D31 | | |
D | 2022-01-29 | Gainsborough | | 1-1 |  | Stafford Rangers | D29 | | |
L | 2022-01-22 | Radcliffe FC |  | 2-0 | | Gainsborough | D28 | | |
W | 2022-01-15 | Gainsborough | | 1-0 |  | Basford United | D27 | | |
L | 2022-01-11 | Nantwich Town | | 2-1 | | Gainsborough | D13 | | |
D | 2022-01-08 | Witton Albion |  | 1-1 | | Gainsborough | D26 | | |
D | 2021-12-27 | Grantham Town | | 1-1 | | Gainsborough | D24 | | |
D | 2021-12-21 | Gainsborough | | 1-1 | | Hyde United | D20 | | |
W | 2021-12-18 | Gainsborough | | 2-0 |  | Bamber Bridge | D23 | | |
D | 2021-12-11 | Gainsborough | | 1-1 |  | Warrington Town | D22 | | |
L | 2021-12-04 | Morpeth Town |  | 2-0 | | Gainsborough | D21 | | |
L | 2021-11-20 | South Shields | | 3-1 | | Gainsborough | D19 | | |
L | 2021-11-06 | FC United of Manchester | | 3-2 | | Gainsborough | D18 | | |
W | 2021-10-23 | Gainsborough | | 1-0 | | Atherton Collieries | D17 | | |
D | 2021-10-16 | Stafford Rangers | | 0-0 | | Gainsborough | D16 | | |
D | 2021-10-09 | Gainsborough | | 1-1 | | Ashton United | D14 | | |
W | 2021-10-02 | Lancaster City | | 0-2 | | Gainsborough | D12 | | |
D | 2021-09-28 | Gainsborough | | 0-0 | | Buxton | D11 | | |
D | 2021-09-25 | Gainsborough | | 1-1 | | Radcliffe FC | D10 | | |
W | 2021-09-18 | Gainsborough | | 1-0 | | Stalybridge Celtic | D15 | | |
L | 2021-09-14 | Basford United | | 2-0 | | Gainsborough | D9 | | |
L | 2021-09-11 | Warrington Town | | 1-0 | | Gainsborough | D8 | | |
W | 2021-09-07 | Gainsborough | | 2-1 | | Morpeth Town | D7 | | |
L | 2021-08-30 | Matlock Town | | 3-0 | | Gainsborough | D6 | | |
W | 2021-08-28 | Gainsborough | | 1-0 | | Whitby Town | D5 | | |
L | 2021-08-24 | Gainsborough | | 0-2 | | Scarborough Athletic | D4 | | |
L | 2021-08-21 | Bamber Bridge | | 5-1 | | Gainsborough | D3 | | |
L | 2021-08-17 | Mickleover | | 2-0 | | Gainsborough | D2 | | |
D | 2021-08-14 | Gainsborough | | 1-1 | | Witton Albion | D1 | | |
